Refractive Foundations

The Library

Important articles, literature, and works related to refractive surgery.

ICL Sizing & Vault Research

Peer-reviewed research on Implantable Collamer Lens (ICL) sizing and vault — including the VAULT and VAULT-OCT AI models — led by the Refractive Foundations team at Parkhurst NuVision. Each links to the journal (DOI), PubMed, and full text where available.

  • Journal of Cataract & Refractive Surgery (JCRS)·2025

    VAULT-OCT: Predicting ICL Postoperative Vault from Anterior-Segment OCT Using Deep Learning

    Matt Hirabayashi, MD, Gurpal Virdi, MD, Nasser T, Abramson A, Parkhurst G

    TL;DR: A deep-learning model predicts the post-op vault from a quick, no-touch OCT scan — aiming to reduce sizing-related ICL exchanges. Powers the latest ICLFit.com.

    DOIPubMed

  • Journal of Cataract & Refractive Surgery (JCRS)·2024

    VAULT: A Novel Image-Based AI Model for Predicting Implantable Collamer Lens Postoperative Vault

    Nasser T, Matt Hirabayashi, MD, Gurpal Virdi, MD, Abramson A, Parkhurst G

    TL;DR: The first AI model to predict the safe vault gap from an image, so the right lens size can be chosen before surgery rather than estimated.

    DOIPubMed

  • Clinical Ophthalmology·2026

    Dynamic Changes in Implantable Collamer Lens Vault and Anterior Chamber Angle Under Varying Lighting Conditions

    Matt Hirabayashi, MD, Cantu E, Abramson A, Gurpal Virdi, MD, Nasser T, Parkhurst G

    TL;DR: Vault is not a single fixed number — it shifts as the pupil changes with lighting, so sizing should target each individual eye, not one universal value.

    DOIPubMedPMC

  • Clinical Ophthalmology·2025

    ICL Exchanges or Explants Due to Sizing in a United States High-Volume Center

    Matt Hirabayashi, MD, Gurpal Virdi, MD, Nasser T, Libfraind L, Zapata E, Abramson A, Parkhurst G

    TL;DR: Measured how often an ICL actually has to be exchanged or removed for sizing at a busy U.S. center — it is uncommon and almost always preventable with better sizing.

    Full text (PDF)DOIPubMedPMC

  • Clinical Ophthalmology·2025

    Clinical Outcomes of Implantable Collamer Lenses for Myopia in Eyes with Anterior Chamber Depth < 3.0 mm at a Single U.S. Center

    Matt Hirabayashi, MD, Gurpal Virdi, MD, Abramson A, Nasser T, Vanrachack A, Parkhurst G

    TL;DR: ICL can work well in shallow eyes (ACD under the usual 3.0 mm cutoff) when sized carefully by an experienced team.

    Full text (PDF)DOIPubMedPMC

  • Cureus·2025

    Accuracy of Reported Sizes of the EVO/EVO+ Visian Implantable Collamer Lenses

    Matt Hirabayashi, MD, Gurpal Virdi, MD, Nasser T, Abramson A, Parkhurst G

    TL;DR: Physically checked how closely manufactured EVO/EVO+ lenses match their labeled sizes — small real-world differences a good sizing tool should account for.

    DOIPubMedPMC

  • Cureus·2026

    Phakic Intraocular Lenses as a Potential Treatment for Pigment Dispersion Syndrome

    Matt Hirabayashi, MD, Cooley A, Shakarchi F, Vanrachack A, Ducker L, Shelby C, Coleman W, Parkhurst G, LoBue S

    TL;DR: Explores using a phakic lens (the same implant family as the ICL) to help pigment dispersion syndrome — hinting these lenses may do more than correct vision.

    DOIPubMedPMC

Research Articles